TM2D1 — TM2 domain containing 1
TM2D1 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TM2D1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Innate lymphoid cells | Mitochondrial Translation Mitochondrial & OxPhos | ABCF1, ARGLU1, ATG12, BAG1, C1orf35, CHCHD1, CHMP5, DNAJC7 +37 more | View in SCUBA |
| Macrophages | Endolysosomal Trafficking Vesicular traficking | ANKRD10, ATP1A1, ATP6V0A1, CHFR, CHML, FAR1, FBXL5, GSAP +21 more | View in SCUBA |
| Smooth muscle cells | Generic maintenance transcripts Housekeeping | CHMP2A, EMP3, HMGN1, MRPL57, NCKAP1, PAIP2, PSMB2, SLC25A5 +5 more | View in SCUBA |
About the gene
| Synonyms | BBP |
|---|---|
| Chromosome | 1: 61681046-61725423 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins |
| Biological process | Apoptosis |
Function
May participate in amyloid-beta-induced apoptosis via its interaction with beta-APP42.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.