TRIM47 — Tripartite motif containing 47
TRIM47 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TRIM47's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Immune Cell Contamination Cell contamination | ANKRD65, CADM1, CD79B, CLEC1A, IL3RA, JDP2, KAZN, MYH11 +2 more | View in SCUBA |
| Smooth muscle cells | Vascular Matrix Secretion ECM remodeling | ARPC1B, BGN, CALHM2, HSPB7, MGP, MXI1, RAB13 | View in SCUBA |
About the gene
| Synonyms | GOA, RNF100 |
|---|---|
| Chromosome | 17: 75874164-75878581 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Predicted intracellular proteins |
| Molecular function | Transferase |
| Biological process | Ubl conjugation pathway |
Function
E3 ubiquitin-protein ligase that mediates the ubiquitination and proteasomal degradation of CYLD
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.