G2/M Mitosis
Gene co-expression module in CD19⁺ B cells
| Category | Cell cycle |
|---|---|
| Genes | 16 |
| Annotation certainty | 5 of 5 |
| Annotation consistency | 14 of 16 genes have a known function matching the annotation |
Why this annotation
CCNB1/2, CDC20, AURKA, PLK1, BUB1, UBE2C, CENPA, DLGAP5, SPC25 are canonical G2/M and mitotic spindle/kinetochore genes. Core coherence. Complements neighbors M79 and M85 (S-phase) as the mitotic arm of the same proliferation program.
Genes
AURKA, BUB1, CCDC34, CCNB1, CCNB2, CDC20, CDKN3, CENPA, DLGAP5, HMGB3, JPT1, KPNA2, PLK1, SPC25, TUBA1C, UBE2C
Most correlated modules
- Mitotic Spindle · correlation 0.95
- Cell Cycle Proliferation · correlation 0.92
- DNA Replication · correlation 0.87
- Mitotic Spindle · correlation 0.85
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.