Mitotic Spindle
Gene co-expression module in CD19⁺ B cells
| Category | Cell cycle |
|---|---|
| Genes | 12 |
| Annotation certainty | 5 of 5 |
| Annotation consistency | 12 of 12 genes have a known function matching the annotation |
Why this annotation
TOP2A, KIF2C, CCNA2, TPX2, AURKB, NUF2, NUSAP1, CDK1, NDC80, CDCA8, PBK are all G2/M mitotic kinetochore/spindle genes. Core mitotic module.
Genes
AURKB, CCNA2, CDCA3, CDCA8, CDK1, KIF2C, NDC80, NUF2, NUSAP1, PBK, TOP2A, TPX2
Most correlated modules
- Mitotic Spindle · correlation 0.97
- G2/M Mitosis · correlation 0.95
- DNA Replication · correlation 0.94
- Cell Cycle Proliferation · correlation 0.94
- Cell Cycle G1/S · correlation 0.91
- DNA Replication · correlation 0.90
- Replication Licensing · correlation 0.88
- DNA Replication · correlation 0.85
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.