DNA Replication
Gene co-expression module in CD19⁺ B cells
| Category | Cell cycle |
|---|---|
| Genes | 12 |
| Annotation certainty | 5 of 5 |
| Annotation consistency | 12 of 12 genes have a known function matching the annotation |
Why this annotation
MCM3/5/7, PCNA, FEN1, GINS2, CDC45, RFC2/4, TK1, DHFR, DHFR are the canonical DNA replication licensing/replisome machinery. Core S-phase module.
Genes
CDC45, CENPH, DHFR, FEN1, GINS2, MCM3, MCM5, MCM7, PCNA, RFC2, RFC4, TK1
Most correlated modules
- Cell Cycle G1/S · correlation 0.97
- DNA Replication · correlation 0.97
- Replication Licensing · correlation 0.96
- G1/S Replication · correlation 0.94
- Cell Cycle Proliferation · correlation 0.93
- RNA Processing · correlation 0.93
- Chromatin Remodeling · correlation 0.91
- DNA Replication · correlation 0.89
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.