High-abundance housekeeping
Gene co-expression module in Enterocytes
| Category | Housekeeping |
|---|---|
| Genes | 10 |
| Annotation certainty | 3 of 5 |
| Annotation consistency | 9 of 11 genes have a known function matching the annotation |
Why this annotation
The module consists of very highly and ubiquitously expressed genes: H3-3A/B, CD63, S100A10/A6, DYNLL1, ARPC3, EIF1, CYSTM1 and EPCAM. Uniform detection at around 94% points to a generic housekeeping or cell-size/library-depth axis rather than a specific program.
Genes
ARPC3, CD63, CYSTM1, DYNLL1, EIF1, EPCAM, H3-3A, H3-3B, S100A10, S100A6
Most correlated modules
- Abundant Transcript Baseline · correlation 0.78
- Redox Detoxification · correlation 0.70
- Nucleolar RNA-binding · correlation 0.60
- Actin cytoskeleton · correlation 0.59
- IFN-gamma immunoproteasome · correlation 0.58
- Surface colonocyte transport · correlation 0.58
- Surface colonocyte differentiation · correlation 0.58
- Metallothionein metal response · correlation 0.58
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.