Lysosomal/ferritin housekeeping
Gene co-expression module in Enterocytes
| Category | Housekeeping |
|---|---|
| Genes | 14 |
| Annotation certainty | 3 of 5 |
| Annotation consistency | 9 of 14 genes have a known function matching the annotation |
Why this annotation
Broadly expressed, highly abundant genes: ferritin (FTL, FTH1), lysosomal genes (PSAP, LAMP1, CD164, CST3), trafficking genes (VAMP8, ITM2B, APLP2), and EDF1, CRIP1 and SPINT2. They are uniformly detected with strong but not core coherence, consistent with a generic housekeeping lysosomal/iron-storage epithelial program.
Genes
APLP2, CD164, CRIP1, CST3, EDF1, FTH1, FTL, GPA33, ITM2B, LAMP1, PRR13, PSAP, SPINT2, VAMP8
Most correlated modules
- Enterocyte lipid metabolism · correlation 0.79
- Mature colonocyte absorptive · correlation 0.79
- Microvillus actin cytoskeleton · correlation 0.72
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.