ATP10D — ATPase phospholipid transporting 10D (putative)
ATP10D belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ATP10D's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Inflammatory activation Immune regulation | ATF7IP2, B3GALT2, COMMD8, GBP3, GFI1, GPR34, MAEA, MGAT1 +7 more | View in SCUBA |
| Innate lymphoid cells | Innate Immune Activation Inflammation | ANKRD11, CNOT2, COA4, DOCK10, IKZF2, NIFK, PRKDC, PSMD11 +13 more | View in SCUBA |
| Macrophages | DNA Damage Repair Stress | ABCC5, ADAM28, AKAP9, AKNA, ATM, BAZ2A, CHD9, CREBRF +27 more | View in SCUBA |
About the gene
| Synonyms | ATPVD, KIAA1487 |
|---|---|
| Chromosome | 4: 47485275-47593486 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Enzymes, Predicted membrane proteins, Transporters |
| Molecular function | Translocase |
| Biological process | Lipid transport, Transport |
Function
Catalytic component of a P4-ATPase flippase complex, which catalyzes the hydrolysis of ATP coupled to the transport of glucosylceramide (GlcCer) from the outer to the inner leaflet of the plasma membrane
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.