CCNDBP1 — Cyclin D1 binding protein 1
CCNDBP1 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CCNDBP1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Cell cycle regulators DNA/chromatin regulation | CCDC28A, CFAP20, EAPP, IFNAR2, LAPTM4A, RBBP4, SH3GLB1 | View in SCUBA |
| Endothelial | TGF-beta ECM Remodeling ECM remodeling | ADAM10, APLP2, CYB5R3, DHRS3, EFEMP2, GNAS, HIPK2, MGST2 +10 more | View in SCUBA |
| Innate lymphoid cells | Mitochondrial OxPhos Mitochondrial & OxPhos | AKR7A2, ANXA6, AP2M1, ARL6IP4, ARPC1B, ATP5MC2, ATP5PB, BSG +21 more | View in SCUBA |
About the gene
| Synonyms | DIP1, GCIP, HHM |
|---|---|
| Chromosome | 15: 43185118-43197177 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Biological process | Cell cycle |
Function
May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.