TPPP3 — Tubulin polymerization promoting protein family member 3
TPPP3 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TPPP3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Glial cells | S100 Glial Activation Activation | CDC42EP5, CREB5, CRIP2, EMP3, S100A10, S100A4, S100A6 | View in SCUBA |
| Pericytes | Pericyte ECM Production ECM production | AEBP1, CALD1, COL14A1, GUCY1B1, LURAP1L, PMP22, SDC2, VCL | View in SCUBA |
| Smooth muscle cells | MHC-I antigen presentation Inflammation | B2M, HLA-A, HLA-B, HLA-C, IFI27, NDUFA4, S100A4, S100A6 +2 more | View in SCUBA |
About the gene
| Synonyms | CGI-38, p20, p25gamma |
|---|---|
| Chromosome | 16: 67389809-67393518 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Regulator of microtubule dynamic that has microtubule bundling activity. Required for embryo implantation; possibly by regulating beta-catenin (By similarity). Also required for decidualization via regulation of beta- catenin.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.