MSI2 — Musashi RNA binding protein 2
MSI2 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MSI2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | Germinal center B-cell B cell maturation | BACH2, BCL6, BPTF, GGA2, MAP4K4, MBD4, MCTP2, NR3C1 +7 more | View in SCUBA |
| CD4⁺ T cells | mRNA stability regulation Immune regulation | APLP2, ARID5B, CARHSP1, GK, GLCCI1, GRAMD4, HIVEP1, METTL8 +12 more | View in SCUBA |
| Endothelial | EC Quiescence Identity Endothelial cell development | ABCC4, ARHGAP5, C1orf115, ENPP4, FAM107A, GIT2, IFNAR2, LRRFIP1 +8 more | View in SCUBA |
| Enterocytes | Transit-amplifying progenitor Epithelial development | CCND2, CLINT1, EHF, ELOVL6, HSD17B12, PKP2, RBM3, SLC38A1 | View in SCUBA |
| Macrophages | Transcriptional Regulation Housekeeping | AATF, ABHD5, ARID3B, DCP1A, GGNBP2, MIA2, NR2C2, NSMAF +18 more | View in SCUBA |
About the gene
| Chromosome | 17: 57255851-57684689 |
|---|---|
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, Disease related genes, Predicted intracellular proteins |
| Molecular function | RNA-binding |
Function
RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.