SCUBA

PTPN3 — Protein tyrosine phosphatase non-receptor type 3

PTPN3 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

PTPN3's module in each cell type

Cell typeModuleShares the module with
Lymphatic endothelialHypoxia Response
Stress
CNTNAP3B, ENOSF1, FBN1, FKBP5, FOXP2, HIF3A, HMCN1, KAT2B +11 moreView in SCUBA
Smooth muscle cellsAdrenergic Neuronal Transcripts
Contractility
ADRA2B, BCAS4, CCDC153, CLYBL, FBXL13, LSMEM2, PPP2R2B, RIMS3 +2 moreView in SCUBA

About the gene

SynonymsPTPH1
Chromosome9: 109375466-109498313
Predicted locationIntracellular
Essential geneNo
Protein classEnzymes, Plasma proteins, Predicted intracellular proteins
Molecular functionHydrolase, Protein phosphatase

Function

May act at junctions between the membrane and the cytoskeleton. Possesses tyrosine phosphatase activity

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.