SIPA1L3 — Signal induced proliferation associated 1 like 3
SIPA1L3 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SIPA1L3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Colonocyte differentiation TFs Chromatin regulation & transcription | AGAP1, ATXN1, DENND1B, DOCK5, GOLIM4, GRAMD2B, HNF4G, JMJD1C +7 more | View in SCUBA |
| Macrophages | MAPK Stress Kinase Inflammatory | ARHGAP26, BRAF, BTBD9, CRY1, CYTH3, EIF2AK3, ESYT2, EXT1 +12 more | View in SCUBA |
About the gene
| Synonyms | KIAA0545, SPAR3 |
|---|---|
| Chromosome | 19: 37907208-38208369 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins |
| Molecular function | GTPase activation |
Function
Plays a critical role in epithelial cell morphogenesis, polarity, adhesion and cytoskeletal organization in the lens
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.