SKI — SKI proto-oncogene
SKI belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SKI's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Endocytic Membrane Remodeling migration & adhesion | ARHGAP23, BNIP2, CDK17, EIF4G2, HERC1, KCTD15, LPCAT1, LRRC8A +4 more | View in SCUBA |
| Mucosal-associated invariant T cell | Tissue Residency Tissue residence | ACSL1, AMFR, CRACDL, DHX36, HES4, IRF8, ITGAE, LZTFL1 +8 more |
About the gene
| Chromosome | 1: 2227388-2310213 |
|---|---|
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins |
Function
May play a role in terminal differentiation of skeletal muscle cells but not in the determination of cells to the myogenic lineage. Functions as a repressor of TGF-beta signaling
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.