CDK17 — Cyclin dependent kinase 17
CDK17 belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CDK17's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Endocytic Membrane Remodeling migration & adhesion | ARHGAP23, BNIP2, EIF4G2, HERC1, KCTD15, LPCAT1, LRRC8A, LUZP1 +4 more | View in SCUBA |
| Gamma-delta T cells | Circadian Clock DNA/chromatin regulation | BHLHE40, CPEB2, CRY1, IRF1, ITPRIP, MEF2D, NR1D2, PRKX +5 more | |
| Lymphatic endothelial | Rho/Ras GTPase Regulation Cytoskeletal | ASAP1, CADPS2, ERC1, ETV6, KIF13A, LDLRAD4, LMBR1, PLEKHG1 +4 more | View in SCUBA |
| Macrophages | Golgi Vesicle Trafficking Vesicular traficking | ARMH3, ATG7, CCDC91, CLASP1, COG5, COMMD10, COP1, DIAPH2 +24 more | View in SCUBA |
| Mucosal-associated invariant T cell | RUNX3 Tissue Identity T cell maturation | B4GALT1, CD44, CHD1, CYLD, EML4, EP300, GPBP1, KMT2E +10 more | |
| Natural Killer cells | TGF-beta Response Immune regulation | ANKRD9, AUTS2, GNA13, MTFP1, N4BP3, RAB5IF, RBM38, TAMALIN +2 more | View in SCUBA |
About the gene
| Synonyms | PCTAIRE2, PCTK2 |
|---|---|
| Chromosome | 12: 96278261-96400480 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Predicted intracellular proteins |
| Molecular function | Kinase, Serine/threonine-protein kinase, Transferase |
Function
May play a role in terminally differentiated neurons. Has a Ser/Thr-phosphorylating activity for histone H1 (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.