BNIP2 — BCL2 interacting protein 2
BNIP2 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
BNIP2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Endocytic Membrane Remodeling migration & adhesion | ARHGAP23, CDK17, EIF4G2, HERC1, KCTD15, LPCAT1, LRRC8A, LUZP1 +4 more | View in SCUBA |
| Gamma-delta T cells | Hypoxia Stress Response Stress | ARIH2, C9orf78, CHD4, FBXO7, HIF1A, HNRNPH1, JADE1, KIF21B +16 more | |
| Macrophages | ER Membrane Homeostasis Housekeeping | ATP6V1A, CANX, CAPZA1, CD164, CMTM6, COPB1, EXOC5, GFM1 +18 more | View in SCUBA |
| Mucosal-associated invariant T cell | NF-κB RNA Regulation RNA processing & translation | ARIH2, ATP1A1, BCLAF1, CALR, COG3, DDX6, EIF4G2, EIF4H +14 more |
About the gene
| Synonyms | BNIP-2, Nip2 |
|---|---|
| Chromosome | 15: 59659146-59689339 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Biological process | Apoptosis |
Function
Implicated in the suppression of cell death. Interacts with the BCL-2 and adenovirus E1B 19 kDa proteins
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.