SLC16A7 — Solute carrier family 16 member 7
SLC16A7 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SLC16A7's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | BCR signaling/maturation B cell maturation | ATP6V0A1, BCL11A, CAMK2D, CD22, CLEC2D, DDHD1, DGKD, IL4R +9 more | View in SCUBA |
| CD4⁺ T cells | Naive T cell T cell development | ABRAXAS1, ATP10A, BACH2, CASP10, FBLN5, GKAP1, HSBP1L1, MCUB +9 more | View in SCUBA |
| Gamma-delta T cells | Actin Cytoskeletal Regulation Cytoskeletal | ACTR2, AP3B1, AP3M1, AZI2, CAPZA1, CEP250, CPSF3, DIDO1 +25 more | |
| Mucosal-associated invariant T cell | T cell Homeostasis T cell maturation | DNAJB14, EPS15, GLG1, INPP5D, MGA, OSBPL3, PHC3, PRP4K +3 more |
About the gene
| Synonyms | MCT2 |
|---|---|
| Chromosome | 12: 59596029-59789855 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Metabolic proteins, Predicted membrane proteins, Transporters |
| Biological process | Symport, Transport |
Function
Proton-coupled monocarboxylate symporter. Catalyzes the rapid transport across the plasma membrane of monocarboxylates such as L- lactate, pyruvate and ketone bodies, acetoacetate, beta-hydroxybutyrate and acetate. Dimerization is functionally required and both subunits work cooperatively in transporting substrate.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.