STRBP — Spermatid perinuclear RNA binding protein
STRBP belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
STRBP's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | Naive B-cell identity B cell maturation | ALOX5AP, CD79B, HLA-DOB, IRF8, NCF1, P2RX5, PLEKHF2, SEC62 +7 more | View in SCUBA |
| Natural Killer cells | ILC1/NK Cytotoxic Cytotoxicity | A1BG, CASK, CLDND1, EIF3G, GZMK, ITM2C, KLRB1, NCF1 +4 more | View in SCUBA |
About the gene
| Synonyms | FLJ11307, ILF3L, SPNR |
|---|---|
| Chromosome | 9: 123109500-123268586 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Developmental protein, DNA-binding, RNA-binding |
| Biological process | Differentiation, Spermatogenesis |
Function
Involved in spermatogenesis and sperm function. Plays a role in regulation of cell growth. Binds to double-stranded DNA and RNA. Binds most efficiently to poly(I:C) RNA than to poly(dI:dC) DNA. Binds also to single-stranded poly(G) RNA. Binds non-specifically to the mRNA PRM1 3'-UTR and adenovirus VA RNA (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.