GZMK — Granzyme K
GZMK belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GZMK's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD8⁺ T cells | Effector Memory CD8 T cell maturation | CLDND1, DENND2D, GIMAP1, GIMAP4, GIMAP7, GPR183, ITM2C, KLRG1 +3 more | View in SCUBA |
| Gamma-delta T cells | Naïve T Cell State T cell maturation | ARL14EP, CCR2, CD27, CD28, CD40LG, CD82, CNN2, CPNE2 +19 more | |
| Mucosal-associated invariant T cell | Mature Effector MAIT T cell maturation | ADD3, ANTKMT, APOBEC3G, CCL5, CXXC5, FHL3, ITGA6, ITGB2 +7 more | |
| Natural Killer cells | ILC1/NK Cytotoxic Cytotoxicity | A1BG, CASK, CLDND1, EIF3G, ITM2C, KLRB1, NCF1, PDCD4 +4 more | View in SCUBA |
About the gene
| Synonyms | PRSS, TRYP2 |
|---|---|
| Chromosome | 5: 55024256-55034570 |
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Enzymes, Predicted secreted proteins |
| Molecular function | Hydrolase, Protease, Serine protease |
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.