TMED5 — Transmembrane p24 trafficking protein 5
TMED5 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TMED5's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Chromatin Remodeling Signaling DNA/chromatin regulation | AKAP13, BPTF, CARNMT1, CCDC6, CFLAR, CLASP1, CLASP2, DOCK10 +23 more | |
| Macrophages | RNA Splicing Regulation Housekeeping | ABCF1, CDC42SE1, CDC5L, CDV3, CEBPZ, DNAJC7, DYNC1LI1, FGFR1OP2 +13 more | View in SCUBA |
About the gene
| Synonyms | CGI-100, p24g2, p24gamma2 |
|---|---|
| Chromosome | 1: 93149742-93180516 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins |
| Biological process | Protein transport, Transport |
Function
Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Required for the maintenance of the Golgi apparatus; involved in protein exchange between Golgi stacks during assembly. Probably not required for COPI-vesicle-mediated retrograde transport
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.