TULP4 — TUB like protein 4
TULP4 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TULP4's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Chromatin transcription regulation DNA/chromatin regulation | ADAM10, CIRBP, CLIP1, CUL9, GRPEL2, HBP1, KDM2A, NCOA3 +10 more | View in SCUBA |
| Enterocytes | Colonocyte differentiation TFs Chromatin regulation & transcription | AGAP1, ATXN1, DENND1B, DOCK5, GOLIM4, GRAMD2B, HNF4G, JMJD1C +7 more | View in SCUBA |
| Gamma-delta T cells | Stress Negative Feedback Immune regulation | ANKRD12, AZIN1, CCDC186, CDKN1A, CYLD, DENND4A, DNAJB6, DUSP10 +7 more |
About the gene
| Synonyms | KIAA1397, TUSP |
|---|---|
| Chromosome | 6: 158232236-158511828 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
| Biological process | Ubl conjugation pathway |
Function
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.