SCUBA

NUSAP1 — Nucleolar and spindle associated protein 1

NUSAP1 belongs to a gene co-expression module in 8 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

NUSAP1's module in each cell type

Cell typeModuleShares the module with
CD19⁺ B cellsMitotic Spindle
Cell cycle		AURKB, CCNA2, CDCA3, CDCA8, CDK1, KIF2C, NDC80, NUF2 +3 moreView in SCUBA
CD8⁺ T cellsMitosis & Cytokinesis
Cell cycle		CDCA2, CEP55, CKAP2L, RACGAP1, SGO1, TACC3, TOP2AView in SCUBA
EndothelialMitotic Spindle
Cell cycle		ASPM, CCNB1, CDK1, CENPE, CENPF, CKAP2, KIF20B, KNSTRN +14 moreView in SCUBA
Gamma-delta T cellsMitosis Execution
Cell cycle		ASF1B, BUB1, CDCA8, CENPE, CENPF, CKS1B, EZH2, MAD2L1 +12 more
Hematopoietic progenitor cellsMitotic Spindle
Cell cycle		ASPM, CDCA8, GTSE1, KIF15, KIF2C, KIF4A, NCAPG, SPC25 +2 more
MacrophagesMitotic Spindle
Cell cycle		ANLN, ASPM, AURKA, BIRC5, CCNA2, CCNB1, CCNB2, CDK1 +14 moreView in SCUBA
Natural Killer cellsMitotic Spindle
Cell cycle		ARL6IP1, ASPM, CENPF, CKS1B, KIF22, MKI67, PTTG1, TACC3 +3 moreView in SCUBA
Smooth muscle cellsMitotic Spindle
Cell cycle		AURKB, CCNA2, CDCA3, CDK1, KIF20A, MKI67, PIMREG, SGO1 +4 moreView in SCUBA

About the gene

SynonymsANKT, BM037, FLJ13421, LNP, PRO0310p1, Q0310, SAPL
Chromosome15: 41320794-41381050
Predicted locationIntracellular
Essential geneNo
Protein classPredicted intracellular proteins
Molecular functionDNA-binding
Biological processCell cycle, Cell division, Mitosis

Function

Microtubule-associated protein with the capacity to bundle and stabilize microtubules (By similarity). May associate with chromosomes and promote the organization of mitotic spindle microtubules around them

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.