AGGF1 — Angiogenic factor with G-patch and FHA domains 1
AGGF1 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
AGGF1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | DNA Damage Repair DNA/chromatin regulation | ANP32A, DCK, DDX46, HADHA, HDDC2, HENMT1, IFNAR1, LYPLA1 +8 more | |
| Macrophages | Resident Mac Niche Tissue homeostasis | ALDH1A1, ARL5A, CD163L1, CD209, CHN2, CLEC4F, CLIC2, CLN6 +22 more | View in SCUBA |
| Mucosal-associated invariant T cell | NF-κB Immune Survival Immune regulation | GOPC, GRAP2, IRF2, LPAR5, MTAP, PDCD10, SENP7, SYNRG +3 more |
About the gene
| Synonyms | FLJ10283, GPATC7, GPATCH7, HSU84971, VG5Q |
|---|---|
| Chromosome | 5: 77029251-77065234 |
| Predicted location | Intracellular, Secreted |
| Essential gene | No |
| Protein class | Disease related genes, Predicted intracellular proteins, Predicted secreted proteins |
| Molecular function | Developmental protein |
| Biological process | Angiogenesis, Differentiation |
Function
Promotes angiogenesis and the proliferation of endothelial cells. Able to bind to endothelial cells and promote cell proliferation, suggesting that it may act in an autocrine fashion
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.