CDH11 — Cadherin 11
CDH11 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CDH11's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Pericytes | Inflammatory Pericyte Activation Developmental | CHN1, EGFL6, NNMT, PROCR, PRRX1, SERPINF1, TDO2, TYMP | View in SCUBA |
| Smooth muscle cells | Mesenchymal Adhesion Program Migration & adhesion | ANTXR1, BAG2, COL12A1, CTSB, FHL3, FSTL3, HEPH, PIM1 +6 more | View in SCUBA |
About the gene
| Synonyms | CAD11, OB |
|---|---|
| Chromosome | 16: 64943753-65126112 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins |
| Biological process | Cell adhesion |
Function
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Required for proper focal adhesion assembly. Involved in the regulation of cell migration
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.