COL5A1 — Collagen type V alpha 1 chain
COL5A1 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
COL5A1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Collagen ECM Production ECM production | AEBP1, ANGPTL2, ANTXR1, CERCAM, CLTC, COL1A1, COL1A2, COL3A1 +12 more | View in SCUBA |
| Pericytes | Fibrillar Collagen Production ECM production | COL1A1, COL1A2, COL3A1, COL6A1, COL6A2, COL6A3, GGT5, PCOLCE +1 more | View in SCUBA |
| Smooth muscle cells | Collagen-Laminin Deposition ECM remodeling | COL5A2, COL6A3, LAMA4, LAMB1, NEGR1, PARVA, PCDH7, RAB32 +4 more | View in SCUBA |
About the gene
| Chromosome | 9: 134641803-134844843 |
|---|---|
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins |
| Molecular function | Heparin-binding |
Function
Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.