COL6A2 — Collagen type VI alpha 2 chain
COL6A2 belongs to a gene co-expression module in 7 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
COL6A2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Inflammatory EC Activation ECM remodeling | C4orf48, CAPG, CD200, COL6A1, IGFBP5, LAMP3, NT5E, OAF +4 more | View in SCUBA |
| Fibroblasts | Basement Membrane ECM ECM production | BSG, COL6A1, COMT, ECE1, ECM1, FNDC3B, LAMB1, LAMC1 +2 more | View in SCUBA |
| Gamma-delta T cells | Innate Stress Signaling Inflammation | AKT3, B4GALT4, BCR, BLOC1S4, CREBRF, DGKQ, ELF2, FAM53B +23 more | |
| Glial cells | Collagen ECM Deposition ECM remodeling | COL15A1, COL18A1, COL1A1, COL28A1, COL4A1, COL4A2, COL5A2, FLNA +2 more | View in SCUBA |
| Macrophages | Hypoxia Stress Response Stress | ACE, AMPD3, APP, ASPH, BCAT1, BEX3, BHLHE41, BNIP3 +34 more | View in SCUBA |
| Pericytes | Fibrillar Collagen Production ECM production | COL1A1, COL1A2, COL3A1, COL5A1, COL6A1, COL6A3, GGT5, PCOLCE +1 more | View in SCUBA |
| Smooth muscle cells | Collagen Biosynthesis ECM remodeling | CALU, COL1A1, COL1A2, COL3A1, COL4A1, COL4A2, COL6A1, EMILIN1 +4 more | View in SCUBA |
About the gene
| Chromosome | 21: 46098112-46132848 |
|---|---|
| Predicted location | Intracellular, Secreted |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins |
| Biological process | Cell adhesion |
Function
Collagen VI acts as a cell-binding protein
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.