SCUBA

COL1A1 — Collagen type I alpha 1 chain

COL1A1 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

COL1A1's module in each cell type

Cell typeModuleShares the module with
FibroblastsCollagen ECM Production
ECM production		AEBP1, ANGPTL2, ANTXR1, CERCAM, CLTC, COL1A2, COL3A1, COL5A1 +12 moreView in SCUBA
Glial cellsCollagen ECM Deposition
ECM remodeling		COL15A1, COL18A1, COL28A1, COL4A1, COL4A2, COL5A2, COL6A2, FLNA +2 moreView in SCUBA
PericytesFibrillar Collagen Production
ECM production		COL1A2, COL3A1, COL5A1, COL6A1, COL6A2, COL6A3, GGT5, PCOLCE +1 moreView in SCUBA
Smooth muscle cellsCollagen Biosynthesis
ECM remodeling		CALU, COL1A2, COL3A1, COL4A1, COL4A2, COL6A1, COL6A2, EMILIN1 +4 moreView in SCUBA

About the gene

SynonymsOI4
Chromosome17: 50184101-50201632
Predicted locationIntracellular, Secreted
Essential geneNo
Protein classCancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins

Function

Type I collagen is a member of group I collagen (fibrillar forming collagen)

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.