ANGPTL2 — Angiopoietin like 2
ANGPTL2 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ANGPTL2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | ECM Fibrotic Remodeling ECM remodeling | ADAMTS7, CD276, CETP, COL18A1, COLGALT1, DDI2, ERO1A, LBH +7 more | View in SCUBA |
| Fibroblasts | Collagen ECM Production ECM production | AEBP1, ANTXR1, CERCAM, CLTC, COL1A1, COL1A2, COL3A1, COL5A1 +12 more | View in SCUBA |
| Smooth muscle cells | Fibroblast-like Activation Activation | CTSK, EFEMP1, LMO3, MICALL2, PDLIM4, PDPN, PTK7 | View in SCUBA |
About the gene
| Synonyms | ARP2, HARP |
|---|---|
| Chromosome | 9: 127087348-127122635 |
| Predicted location | Intracellular, Secreted |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted secreted proteins |
Function
Induces sprouting in endothelial cells through an autocrine and paracrine action
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.