GJA5 — Gap junction protein alpha 5
GJA5 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GJA5's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Inflammatory Angiogenesis Inflammation | AZIN1, DHH, FBLN5, FILIP1L, ITSN2, NUDT4, OCIAD2, PIK3C2B +6 more | View in SCUBA |
| Pericytes | Arterial Pericyte Identity Developmental | ATP13A3, BMX, FBLN2, KCTD12, LTC4S, PLLP, SEMA3G, TMEM100 +1 more | View in SCUBA |
About the gene
| Synonyms | CX40 |
|---|---|
| Chromosome | 1: 147756199-147773362 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters |
Function
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.