NCR2 — Natural cytotoxicity triggering receptor 2
NCR2 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
NCR2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Innate lymphoid cells | NK Activating Receptors Cytotoxicity | CAT, CRACDL, ELAPOR1, FLT3LG, KLRK1, KRTCAP2, LTA4H, MFSD10 +7 more | View in SCUBA |
| Natural Killer cells | Tissue-Resident NK Gut residency | ADRB1, CAMK4, GPR34, GPR55, ITGAE, LRRC25, MYO1E, S100A13 +2 more | View in SCUBA |
About the gene
| Synonyms | CD336, LY95, NK-p44 |
|---|---|
| Chromosome | 6: 41335608-41350889 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | CD markers, Predicted membrane proteins |
| Molecular function | Receptor |
Function
Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.