MFSD10 — Major facilitator superfamily domain containing 10
MFSD10 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MFSD10's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | ER stress UPR Protein processing & ER | CCT2, CDK2AP2, CRELD2, DDX39A, DNAJB11, DSTN, EIF5A, GPSM3 +9 more | View in SCUBA |
| Gamma-delta T cells | T-bet Effector Differentiation T cell maturation | ABHD17A, BCL7C, CAPNS1, CHST12, DGKZ, EFHD2, FMNL1, GNAI2 +15 more | |
| Innate lymphoid cells | NK Activating Receptors Cytotoxicity | CAT, CRACDL, ELAPOR1, FLT3LG, KLRK1, KRTCAP2, LTA4H, MLLT3 +7 more | View in SCUBA |
| Macrophages | Glycolytic Redox Metabolism Lipid metabolism | AGPAT2, ANXA5, ATP6V1F, BCKDK, BRI3, C1orf122, CLIC1, ELOC +18 more | View in SCUBA |
| Mucosal-associated invariant T cell | RNA Biogenesis & Folding Housekeeping | ADH5, CCT3, CTDSP1, FAM117A, FKBP1A, FKBP8, LSM4, MAT2B +6 more |
About the gene
| Synonyms | IT10C3, TETRAN |
|---|---|
| Chromosome | 4: 2930561-2934834 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins |
| Biological process | Apoptosis, Transport |
Function
Probable organic anion transporter which may serve as a transporter for some non-steroidal anti-inflammatory drugs (NSAIDs) as well as other organic anions across the luminal membranes of renal proximal tubules at the final excretion step into the urine
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.