RBIS — Ribosomal biogenesis factor
RBIS belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
RBIS's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | ATP Synthase Complex Mitochondrial & OxPhos | ATP5F1D, ATP5F1E, ATP5MC2, ATP5MC3, ATP5MF, ATP5MG, ATP5MK, ATP5PD +23 more | |
| Innate lymphoid cells | Septin Cytoskeleton Cytoskeleton & motility | ATP6V0C, C17orf49, CIAO2A, COX16, DARS1, DDOST, GET3, H2AC6 +18 more | View in SCUBA |
| Mucosal-associated invariant T cell | ATP Synthase Complex Mitochondrial & OxPhos | ARL6IP4, ATP5F1E, ATP5ME, ATP5MK, COMMD6, COPS9, COX7C, HAX1 +3 more | |
| Smooth muscle cells | Histone Variant Chromatin DNA/chromatin regulation | ATP5MJ, ATP5MK, ECRG4, H2AZ1, H2AZ2, H3-3A, H3-3B, MACROH2A1 +6 more | View in SCUBA |
About the gene
| Synonyms | C8orf59 |
|---|---|
| Chromosome | 8: 85214048-85220421 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Trans-acting factor in ribosome biogenesis required for efficient 40S and 60S subunit production
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.