SLC25A36 — Solute carrier family 25 member 36
SLC25A36 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SLC25A36's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Glial cells | ENS Developmental TFs Development | ERBIN, FRMD3, HAND2, LRRC4C, MAP4K4, PYGL, SEC11C, TBX3 +2 more | View in SCUBA |
| Macrophages | ER-Golgi Trafficking Vesicular traficking | ADD1, AFTPH, AZIN1, COPA, DYNC1H1, HNRNPC, JOSD1, LCP2 +23 more | View in SCUBA |
About the gene
| Synonyms | FLJ10618, PNC2 |
|---|---|
| Chromosome | 3: 140941830-140980995 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters |
| Biological process | Transport |
Function
Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria. Selectively transports cytosine, guanosine, inosine and uridine (deoxy)nucleoside mono-, di-, and triphosphates by antiport mechanism. Catalyzes uniport at much lower rate. May import (deoxy)nucleoside triphosphates in exchange for intramitochondrial (deoxy)nucleoside mono- and diphosphates, thus providing precursors necessary for de novo synthesis of mitochondrial DNA and RNA while exporting products of their catabolism. Participates in mitochondrial genome maintenance, regulation of mitochondrial membrane potential and mitochondrial respiration
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.