STARD13 — StAR related lipid transfer domain containing 13
STARD13 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
STARD13's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | NFAT-cAMP Signaling Inflammatory | ACKR3, ADGRE2, ANKRD28, CHSY1, CREM, ELL2, FRMD4A, GPCPD1 +3 more | View in SCUBA |
| Lymphatic endothelial | Rho/Ras GTPase Regulation Cytoskeletal | ASAP1, CADPS2, CDK17, ERC1, ETV6, KIF13A, LDLRAD4, LMBR1 +4 more | View in SCUBA |
| Monocytes | Efferocytosis Tissue Macrophage Lysosomal & pahgocytosis | ADORA3, AKR1B1, CPM, FCHO2, GPR34, MERTK, PDK4, SLC1A3 | View in SCUBA |
About the gene
| Synonyms | ARHGAP37, DLC2, GT650, LINC00464 |
|---|---|
| Chromosome | 13: 33103137-33350630 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Metabolic proteins, Plasma proteins, Predicted intracellular proteins |
| Molecular function | GTPase activation |
Function
GTPase-activating protein for RhoA, and perhaps for Cdc42. May be involved in regulation of cytoskeletal reorganization, cell proliferation and cell motility. Acts a tumor suppressor in hepatocellular carcinoma cells.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.