GPCPD1 — Glycerophosphocholine phosphodiesterase 1
GPCPD1 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GPCPD1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | TCR signaling activation TCR/AP1/NFKb pathway | CNST, CORO1B, DAPP1, ECI1, FAAH2, FCMR, KLHL24, MLLT3 +8 more | View in SCUBA |
| Fibroblasts | NFAT-cAMP Signaling Inflammatory | ACKR3, ADGRE2, ANKRD28, CHSY1, CREM, ELL2, FRMD4A, RCAN1 +3 more | View in SCUBA |
| Macrophages | Transcriptional Repression Housekeeping | AKAP8, ANKRD11, ARIH2, BACH1, CCNT2, CDK13, CEP95, CSNK1D +23 more | View in SCUBA |
| Monocytes | Wnt/AP-1 Activation Inflammatory | B4GALT1, BZW1, CHD1, CTNNB1, ETF1, FOSL2, GABARAPL1, PNPLA8 +2 more | View in SCUBA |
| Mucosal-associated invariant T cell | Immune Synapse Signaling TCR Signaling | APC, ARHGAP26, ASXL2, CD46, CPSF2, DOCK8, EEA1, EIF4G3 +21 more |
About the gene
| Synonyms | GDE5, GDPD6, KIAA1434 |
|---|---|
| Chromosome | 20: 5544439-5611006 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Predicted intracellular proteins |
| Molecular function | Hydrolase |
Function
May be involved in the negative regulation of skeletal muscle differentiation, independently of its glycerophosphocholine phosphodiesterase activity
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.