DUSP23 — Dual specificity phosphatase 23
DUSP23 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
DUSP23's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Venular Inflammatory Activation Inflammation | ACKR1, AIM2, ARL4C, ASAP3, BNC2, CFP, FAM3D, IL18R1 +8 more | View in SCUBA |
| Gamma-delta T cells | Mitochondrial OxPhos Mitochondrial & OxPhos | ADSL, AP1S1, CD151, COMTD1, COX5A, DDT, DNPH1, ETFB +20 more | |
| Pericytes | UC Inflammatory Activation Inflammatory | BDKRB2, CD200, CSF2RB, HLA-DQA1, MEOX1, NR5A2, PCDH17, RGCC +3 more | View in SCUBA |
About the gene
| Synonyms | DUSP25, FLJ20442 |
|---|---|
| Chromosome | 1: 159780932-159782543 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Predicted intracellular proteins |
| Molecular function | Hydrolase, Protein phosphatase |
Function
Protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues. In vitro, it can dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10) in vitro. Able to enhance activation of JNK and p38 (MAPK14)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.