CD200 — CD200 molecule
CD200 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CD200's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | Naive B cell B cell maturation | ABCB1, ABCB4, BTLA, C1orf162, COL19A1, DSP, FCER2, IGHD +15 more | View in SCUBA |
| CD4⁺ T cells | CD200 immunoregulation Immune regulation | B3GNT2, CAV1, CD79A, CH25H, CHGB, DUOX1, ELF2, EVI5 +23 more | View in SCUBA |
| Endothelial | Inflammatory EC Activation ECM remodeling | C4orf48, CAPG, COL6A1, COL6A2, IGFBP5, LAMP3, NT5E, OAF +4 more | View in SCUBA |
| Lymphatic endothelial | NF-κB Inflammatory Activation Inflammation | ACHE, ANKLE2, CXCL1, CXCL8, HMGA1, ICOSLG, NFKB2, NOD2 +9 more | View in SCUBA |
| Pericytes | UC Inflammatory Activation Inflammatory | BDKRB2, CSF2RB, DUSP23, HLA-DQA1, MEOX1, NR5A2, PCDH17, RGCC +3 more | View in SCUBA |
About the gene
| Synonyms | MOX1, MOX2, MRC, OX-2 |
|---|---|
| Chromosome | 3: 112332347-112362812 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | CD markers, Predicted intracellular proteins, Predicted membrane proteins |
Function
Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.