LRRC59 — Leucine rich repeat containing 59
LRRC59 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
LRRC59's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Anabolic Activation Response Housekeeping | ABHD5, ATF4, ATP6V0C, ATP6V1G1, BCL7B, BUD31, CALM2, CHRAC1 +26 more | |
| Goblet cells | UPR Chaperone Response Stress | CALR, CRELD2, GMPPB, MANF, NUCB2, P4HB, PDIA3, PDIA4 +2 more | View in SCUBA |
| Macrophages | Proteasome UPS Housekeeping | ATP6V1D, ATP6V1E1, BAX, C1orf43, COX7A2L, DCUN1D5, DNAJC15, DNAJC8 +28 more | View in SCUBA |
About the gene
| Synonyms | FLJ21675, PRO1855 |
|---|---|
| Chromosome | 17: 50375059-50397523 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins, Transporters |
Function
Required for nuclear import of FGF1, but not that of FGF2. Might regulate nuclear import of exogenous FGF1 by facilitating interaction with the nuclear import machinery and by transporting cytosolic FGF1 to, and possibly through, the nuclear pores
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.