KIF11 — Kinesin family member 11
KIF11 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
KIF11's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | Mitotic Spindle Cell cycle | CENPF, GTSE1, HMMR, KIF22, KIFC1, NCAPG, SGO1, SHCBP1 +3 more | View in SCUBA |
| CD8⁺ T cells | Spindle Bipolarity Cytokinesis Cell cycle | ANLN, ARHGAP11A, BUB1B, C21orf58, CIT, DIAPH3, ECT2, KIF15 +4 more | View in SCUBA |
| Goblet cells | Chromosome Segregation Cell cycle | ANLN, CDCA2, CDCA8, CKAP2L, HJURP, KIFC1, NCAPG, NDC80 +3 more | View in SCUBA |
About the gene
| Synonyms | Eg5, HKSP, KNSL1, TRIP5 |
|---|---|
| Chromosome | 10: 92574105-92655395 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Motor protein |
| Biological process | Cell cycle, Cell division, Mitosis |
Function
Motor protein required for establishing a bipolar spindle and thus contributing to chromosome congression during mitosis. Required in non-mitotic cells for transport of secretory proteins from the Golgi complex to the cell surface.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.