NCAPG — Non-SMC condensin I complex subunit G
NCAPG belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
NCAPG's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | Mitotic Spindle Cell cycle | CENPF, GTSE1, HMMR, KIF11, KIF22, KIFC1, SGO1, SHCBP1 +3 more | View in SCUBA |
| CD8⁺ T cells | FOXM1-driven G2/M Cell cycle | CENPW, FOXM1, MKI67, NDC80, NEIL3, PBK, RCCD1 | View in SCUBA |
| Goblet cells | Chromosome Segregation Cell cycle | ANLN, CDCA2, CDCA8, CKAP2L, HJURP, KIF11, KIFC1, NDC80 +3 more | View in SCUBA |
| Hematopoietic progenitor cells | Mitotic Spindle Cell cycle | ASPM, CDCA8, GTSE1, KIF15, KIF2C, KIF4A, NUSAP1, SPC25 +2 more |
About the gene
| Synonyms | CAP-G, FLJ12450, hCAP-G, YCG1 |
|---|---|
| Chromosome | 4: 17810979-17844865 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Predicted intracellular proteins |
| Biological process | Cell cycle, Cell division, DNA condensation, Mitosis |
Function
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.