SCUBA

KIFC1 — Kinesin family member C1

KIFC1 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

KIFC1's module in each cell type

Cell typeModuleShares the module with
CD19⁺ B cellsMitotic Spindle
Cell cycle
CENPF, GTSE1, HMMR, KIF11, KIF22, NCAPG, SGO1, SHCBP1 +3 moreView in SCUBA
CD8⁺ T cellsCDK1-Aurora Kinase Mitosis
Cell cycle
AURKB, BIRC5, CCNA2, CDK1, CDKN3, CKS1B, KIF22, MAD2L1 +2 moreView in SCUBA
Goblet cellsChromosome Segregation
Cell cycle
ANLN, CDCA2, CDCA8, CKAP2L, HJURP, KIF11, NCAPG, NDC80 +3 moreView in SCUBA

About the gene

SynonymsHSET, KNSL2
Chromosome6: 33391823-33409896
Predicted locationIntracellular
Essential geneNo
Protein classPlasma proteins, Predicted intracellular proteins
Molecular functionMotor protein
Biological processCell cycle, Cell division, Mitosis

Function

Minus end-directed microtubule-dependent motor required for bipolar spindle formation. May contribute to movement of early endocytic vesicles (By similarity). Regulates cilium formation and structure (By similarity).

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.