GTSE1 — G2 and S-phase expressed 1
GTSE1 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GTSE1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | Mitotic Spindle Cell cycle | CENPF, HMMR, KIF11, KIF22, KIFC1, NCAPG, SGO1, SHCBP1 +3 more | View in SCUBA |
| CD8⁺ T cells | Mitotic Spindle Cell cycle | ASPM, BUB1, CENPA, CENPE, CENPF, DLGAP5, HMMR, KIF14 +6 more | View in SCUBA |
| Hematopoietic progenitor cells | Mitotic Spindle Cell cycle | ASPM, CDCA8, KIF15, KIF2C, KIF4A, NCAPG, NUSAP1, SPC25 +2 more |
About the gene
| Synonyms | B99, GTSE-1, Lnc_bc060912 |
|---|---|
| Chromosome | 22: 46296870-46330810 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
Function
May be involved in p53-induced cell cycle arrest in G2/M phase by interfering with microtubule rearrangements that are required to enter mitosis. Overexpression delays G2/M phase progression
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.