LMO2 — LIM domain only 2
LMO2 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
LMO2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Hematopoietic progenitor cells | Erythroid Glycolysis Erythropoietic | CMBL, ENO1, GAPDH, GYPC, LY6E, MAP7, NENF, PKM +3 more | |
| Lymphatic endothelial | Lymphatic EC Identity endothelial development | ATP6AP2, BEX3, CD151, FDPS, GNG11, MGST3, NAA38, POLR2L +2 more | View in SCUBA |
| Pericytes | MHC-II Antigen Presentation Inflammatory | CD74, CIITA, CYYR1, FLI1, HLA-DMA, HLA-DMB, HLA-DPA1, HLA-DPB1 +4 more | View in SCUBA |
About the gene
| Synonyms | RBTN2, RBTNL1, RHOM2, TTG2 |
|---|---|
| Chromosome | 11: 33858576-33892076 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins |
Function
Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.