SCUBA

NAA38 — N-alpha-acetyltransferase 38, NatC auxiliary subunit

NAA38 belongs to a gene co-expression module in 10 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

NAA38's module in each cell type

Cell typeModuleShares the module with
CD19⁺ B cellsMitochondrial Redox
Mitochondrial & OxPhos
COMTD1, GLRX5, MRPL37, MRPL51, PRDX2, PRDX3, PTTG1, RBX1 +1 moreView in SCUBA
CD8⁺ T cellsMitochondrial ETC/OxPhos
Mitochondrial & OxPhos
AP2S1, BAX, COX6A1, ERH, HSD17B10, LSM2, MAD2L2, MEA1 +7 moreView in SCUBA
Gamma-delta T cellsComplex I Assembly
Mitochondrial & OxPhos
AKR7A2, AP2S1, BLOC1S1, DCTN2, HSD17B10, LAMTOR2, MGMT, MRPL34 +13 more
Goblet cellsMitochondrial OxPhos
Mitochondrial & OxPhos
CYC1, MAZ, NDUFV1, PFKL, PPP1R1B, PXMP2, TECRView in SCUBA
Hematopoietic progenitor cellsGeneral Metabolic Housekeeping
Housekeeping
ACSM3, DTD1, EREG, FXN, SERPINE2, SLC39A3, SLC39A8
Innate lymphoid cellsActin Cytoskeletal Regulation
Cytoskeleton & motility
AQP3, CCDC57, CLPTM1, COTL1, DCAF11, GSN, GYG1, MZT2B +7 moreView in SCUBA
Lymphatic endothelialLymphatic EC Identity
endothelial development
ATP6AP2, BEX3, CD151, FDPS, GNG11, LMO2, MGST3, POLR2L +2 moreView in SCUBA
MacrophagesMitotic Spindle Assembly
Cell cycle
ACTL6A, AKR7A2, ANP32E, BOLA3, BUB3, CCDC167, CENPW, CENPX +34 moreView in SCUBA
Mucosal-associated invariant T cellMitochondrial Housekeeping
Mitochondrial & OxPhos
ARPC3, DUT, GNB2, GPSM3, LSM2, NDUFB10, PLEKHJ1, REX1BD +7 more
PericytesActin-ERM Migration
Cytoskeletal
CRIP2, DIAPH1, FKBP1A, FXYD5, ITGA5, MRPL17, MSN, RDXView in SCUBA

About the gene

SynonymsLSMD1, MGC14151, PFAAP2
Chromosome17: 7856685-7885238
Predicted locationIntracellular
Essential geneYes
Protein classEssential proteins, Predicted intracellular proteins

Function

Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues. N-terminal acetylation protects proteins from ubiquitination and degradation by the N-end rule pathway.

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.