NBEAL2 — Neurobeachin like 2
NBEAL2 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
NBEAL2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | Atypical memory B cell B cell maturation | FCRL5, FGR, HCK, HEXA, HMOX1, ITGAX, LRRK2, MED13L +5 more | View in SCUBA |
| CD4⁺ T cells | Leukocyte Motility migration & adhesion | ATP2A3, HSH2D, LRP12, LZTFL1, MYO1G, MYO9B, PPARG, TBC1D31 +1 more | View in SCUBA |
| Gamma-delta T cells | TCR Activation Signaling TCR Signaling | ADCY7, ATP2B4, CYFIP2, DIAPH1, GK5, GLG1, ITGAL, NFATC3 +4 more | |
| Monocytes | Pentose Phosphate Pathway Innate immunity | ACAP1, AP5B1, CCDC69, CCND3, CITED4, CORO2A, DYSF, EIF4E3 +4 more | View in SCUBA |
About the gene
| Synonyms | KIAA0540 |
|---|---|
| Chromosome | 3: 46979666-47009704 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins |
Function
Probably involved in thrombopoiesis. Plays a role in the development or secretion of alpha-granules, that contain several growth factors important for platelet biogenesis
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.