GK5 — Glycerol kinase 5
GK5 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GK5's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | TCR Activation Signaling TCR Signaling | ADCY7, ATP2B4, CYFIP2, DIAPH1, GLG1, ITGAL, NBEAL2, NFATC3 +4 more | |
| Macrophages | Inflammatory Monocyte Activation Inflammatory | ANPEP, AQP9, CD300E, CD82, CLEC5A, CXXC5, DDX60L, DHRS9 +25 more | View in SCUBA |
| Natural Killer cells | Cytotoxic NK Maturation Cytotoxicity | ADGRG1, AKR1C3, CXCR2, FCGR3A, FGFBP2, LGR6, MTSS1, PRF1 +4 more | View in SCUBA |
About the gene
| Synonyms | MGC40579 |
|---|---|
| Chromosome | 3: 142157527-142225592 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Predicted intracellular proteins |
| Molecular function | Kinase, Transferase |
| Biological process | Glycerol metabolism |
Function
Skin-specific kinase that plays a key role in glycerol metabolism, catalyzing its phosphorylation to produce sn-glycerol 3- phosphate. Involved in skin-specific regulation of sterol regulatory element-binding protein (SREBP) processing and lipid biosynthesis
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.