NFASC — Neurofascin
NFASC belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
NFASC's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Complement-producing Fibroblast Inflammatory | ANK2, C3, CLSTN3, CYP7B1, DAAM1, DHRS3, GUCY1A1, GUCY1B1 +8 more | View in SCUBA |
| Pericytes | Pericyte Identity Differentiation Developmental | ADAMTS5, ARHGAP15, EPB41L2, GUCY1A1, INPP4B, LGI4, LMOD1, MAP1LC3A +11 more | View in SCUBA |
| Smooth muscle cells | Mural/Pericyte Identity Development | C1QTNF1, EBF1, FRMD4A, FRY, ITGA7, LGALSL, LGI4, MCAM +6 more | View in SCUBA |
About the gene
| Synonyms | FLJ46866, KIAA0756, NF, NRCAML |
|---|---|
| Chromosome | 1: 204828651-205022822 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins |
| Biological process | Cell adhesion |
Function
Cell adhesion, ankyrin-binding protein which may be involved in neurite extension, axonal guidance, synaptogenesis, myelination and neuron-glial cell interactions
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.