PI16 — Peptidase inhibitor 16
PI16 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PI16's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Arterial EC Identity Endothelial cell development | AFAP1L2, BMP4, CFAP36, FUT8, ITPR2, JAG1, LTBP4, NEBL +6 more | View in SCUBA |
| Fibroblasts | PI16+ Fibroblast Identity ECM production | AADACL2, ADAMTSL4, ARHGAP29, C16orf89, CADM3, CD248, CLEC3B, CYP4B1 +10 more | View in SCUBA |
| Mucosal-associated invariant T cell | Mucosal MAIT Homing migration & adhesion | BLK, BRD9, CCR6, DSEL, ERN1, FUT7, LGALS3, LPAR6 +5 more |
About the gene
| Synonyms | CD364, dJ90K10.5, MGC45378, MSMBBP |
|---|---|
| Chromosome | 6: 36948263-36964837 |
| Predicted location | Membrane, Secreted |
| Essential gene | No |
| Protein class | CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins |
| Molecular function | Protease inhibitor |
Function
May inhibit cardiomyocyte growth
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.