PILRB — Paired immunoglobin like type 2 receptor beta
PILRB belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PILRB's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | EOMES Effector Program T cell maturation | AGK, ANKZF1, ATG16L2, C6orf120, CARD8, CBX1, CDK5RAP3, CENPT +25 more | |
| Mucosal-associated invariant T cell | Chromatin Maintenance State DNA/chromatin regulation | ATRX, DYRK2, GART, KIF2A, RBL2, S1PR5, SH2D1A, THEMIS2 +3 more | |
| Natural Killer cells | IFN-stimulated NK Inflammation | AKNA, APOL6, ATM, CTSC, ITGAL, MBP, MXD1, PTPRC +4 more | View in SCUBA |
About the gene
| Synonyms | FDFACT1, FDFACT2 |
|---|---|
| Chromosome | 7: 100352176-100367831 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins |
| Molecular function | Receptor |
Function
Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PILRB is thought to act as a cellular signaling activating receptor that associates with ITAM-bearing adapter molecules on the cell surface
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.