KIF2A — Kinesin family member 2A
KIF2A belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
KIF2A's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Butyrophilin gd Activation TCR Signaling | ABI1, ADD3, ANXA6, ARHGAP1, ARHGAP25, ARHGAP30, ARHGEF2, BTN3A1 +16 more | |
| Innate lymphoid cells | Cell Cycle Regulation Cell cycle | CDKN1B, FLI1, GLG1, RAD21, TAF15, TBRG1 | View in SCUBA |
| Mucosal-associated invariant T cell | Chromatin Maintenance State DNA/chromatin regulation | ATRX, DYRK2, GART, PILRB, RBL2, S1PR5, SH2D1A, THEMIS2 +3 more |
About the gene
| Synonyms | HK2, KIF2 |
|---|---|
| Chromosome | 5: 62306162-62391025 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Developmental protein, Motor protein |
| Biological process | Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis |
Function
Plus end-directed microtubule-dependent motor required for normal brain development. May regulate microtubule dynamics during axonal growth. Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate. Required for normal spindle dynamics during mitosis. Promotes spindle turnover. Implicated in formation of bipolar mitotic spindles. Has microtubule depolymerization activity.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.